Activity of Simulated Human Dosage Regimens of Meropenem and Vaborbactam against Carbapenem-Resistant Enterobacteriaceae in an In Vitro Hollow-Fiber Model

The objective of these studies was to evaluate the exposures of meropenem and vaborbactam that would produce antibacterial activity and prevent resistance development in carbapenem-resistant Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae strains when tested at an inoculum of...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Sabet, Mojgan, Tarazi, Ziad, Rubio-Aparicio, Debora, Nolan, Thomas G., Parkinson, Jonathan, Lomovskaya, Olga, Dudley, Michael N., Griffith, David C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2018
Témata:
Experimental Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5786802/
https://ncbi.nlm.nih.gov/pubmed/29133570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01969-17
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