Clinical Evolution of New Delhi Metallo-β-Lactamase (NDM) Optimizes Resistance under Zn(II) Deprivation

Carbapenem-resistant Enterobacteriaceae (CRE) are rapidly spreading and taking a staggering toll on all health care systems, largely due to the dissemination of genes coding for potent carbapenemases. An important family of carbapenemases are the Zn(II)-dependent β-lactamases, known as metallo-β-lac...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Bahr, Guillermo, Vitor-Horen, Luisina, Bethel, Christopher R., Bonomo, Robert A., González, Lisandro J., Vila, Alejandro J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2017
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740384/
https://ncbi.nlm.nih.gov/pubmed/29038264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01849-17
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