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A CTG Clade Candida Yeast Genetically Engineered for the Genotype-Phenotype Characterization of Azole Antifungal Resistance in Human-Pathogenic Yeasts

A strain of the opportunistic pathogenic yeast Candida lusitaniae was genetically modified for use as a cellular model for assessing by allele replacement the impact of lanosterol C14α-demethylase ERG11 mutations on azole resistance. Candida lusitaniae was chosen because it is susceptible to azole a...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Accoceberry, Isabelle, Rougeron, Amandine, Biteau, Nicolas, Chevrel, Pauline, Fitton-Ouhabi, Valérie, Noël, Thierry
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740319/
https://ncbi.nlm.nih.gov/pubmed/29038279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01483-17
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