Two missense mutations, E123Q and K151E, identified in the ERG11 allele of an azole-resistant isolate of Candida kefyr recovered from a stem cell transplant patient for acute myeloid leukemia

We report on the first cloning and nucleotide sequencing of an ERG11 allele from a clinical isolate of Candida kefyr cross-resistant to azole antifungals. It was recovered from a stem cell transplant patient, in an oncohematology unit exhibiting unexpected high prevalence of C. kefyr. Two amino acid...

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Bibliographic Details
Main Authors: Couzigou, Célia, Gabriel, Frédéric, Biteau, Nicolas, Fitton-Ouhabi, Valérie, Noël, Thierry, Accoceberry, Isabelle
Format: Artigo
Language:Inglês
Published: Elsevier 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4052357/
https://ncbi.nlm.nih.gov/pubmed/24936404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mmcr.2014.04.002
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