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Detection of Mycobacterium tuberculosis pncA Mutations by the Nipro Genoscholar PZA-TB II Assay Compared to Conventional Sequencing

Pyrazinamide (PZA) is a standard component of first-line treatment regimens for Mycobacterium tuberculosis and is included in treatment regimens for drug-resistant M. tuberculosis whenever possible. Therefore, it is imperative that susceptibility to PZA be assessed reliably prior to the initiation o...

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Publicado en:Antimicrob Agents Chemother
Main Authors: Willby, Melisa J., Wijkander, Maria, Havumaki, Joshua, Johnson, Kartee, Werngren, Jim, Hoffner, Sven, Denkinger, Claudia M., Posey, James E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740318/
https://ncbi.nlm.nih.gov/pubmed/29084743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01871-17
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