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Characterization of pncA Mutations and Prediction of PZA Resistance in Mycobacterium tuberculosis Clinical Isolates From Chongqing, China

Pyrazinamide (PZA) is widely used to treat drug-sensitive or multidrug resistance tuberculosis. However, conventional PZA susceptibility tests of clinical isolates are rather difficult because of the requirement of acid pH. Since resistance to pyrazinamide is primary mediated by mutation of pncA, an...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Front Microbiol
Main Authors: Li, Kun, Yang, Zhongping, Gu, Jing, Luo, Ming, Deng, Jiaoyu, Chen, Yaokai
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2021
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7832174/
https://ncbi.nlm.nih.gov/pubmed/33505367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.594171
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