Glutaminolysis drives membrane trafficking to promote invasiveness of breast cancer cells

The role of glutaminolysis in providing metabolites to support tumour growth is well-established, but the involvement of glutamine metabolism in invasive processes is yet to be elucidated. Here we show that normal mammary epithelial cells consume glutamine, but do not secrete glutamate. Indeed, low...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Dornier, Emmanuel, Rabas, Nicolas, Mitchell, Louise, Novo, David, Dhayade, Sandeep, Marco, Sergi, Mackay, Gillian, Sumpton, David, Pallares, Maria, Nixon, Colin, Blyth, Karen, Macpherson, Iain R., Rainero, Elena, Norman, Jim C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740148/
https://ncbi.nlm.nih.gov/pubmed/29269878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-02101-2
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