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Cancer cells with trapped nuclei cut their way through the extracellular matrix

When an invading cancer cell attempts to pass through a hole in the extracellular matrix (ECM) which is too small for its nucleus, this generates physical tension. This tension is sensed by a nucleus–centrosome connection that activates trafficking of endosomal vesicles containing the matrix metallo...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Commun
Egile Nagusiak: Dornier, Emmanuel, Norman, Jim C.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6160491/
https://ncbi.nlm.nih.gov/pubmed/30262828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-06351-6
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