Oridonin synergistically enhances JQ1-triggered apoptosis in hepatocellular cancer cells through mitochondrial pathway

Bromodomain and Extra-Terminal Domain (BET) inhibitors, such as JQ1 have emerged as novel drug candidates and are being enthusiastically pursued in clinical trials for the treatment of cancer. However, many solid cancers are resistance to BET inhibitors. To explore methods for improving the therapeu...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Zhang, Hua-Peng, Li, Gong-Quan, Guo, Wen-Zhi, Chen, Guang-Hui, Tang, Hong-Wei, Yan, Bing, Li, Jie, Zhang, Jia-Kai, Wen, Pei-Hao, Wang, Zhi-Hui, Lv, Jian-Feng, Zhang, Shui-Jun
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739777/
https://ncbi.nlm.nih.gov/pubmed/29290992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21880
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