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Mitochondrial ROS contribute to oridonin-induced HepG2 apoptosis through PARP activation

Oridonin, the main active constituent of Rabdosia rubescens, is known to exert antitumor activity via the induction of apoptosis in numerous types of human cancer cells. However, the underlying regulatory mechanisms of mitochondrial ROS in oridonin-induced HepG2 apoptosis remain largely unknown, due...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Liu, Xiaoning, Kang, Jingjing, Wang, Hui, Huang, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5778846/
https://ncbi.nlm.nih.gov/pubmed/29435014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2017.7665
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