Exacerbation of diabetic cardiac hypertrophy in OVE26 mice by angiotensin II is associated with JNK/c-Jun/miR-221-mediated autophagy inhibition

Both diabetes and angiotensin II (Ang II) excess trigger cardiac remodeling and dysfunction, and diabetic cardiomyopathy. We hypothesized that cardiac hypertrophy associated with the development of diabetic cardiomyopathy is worsened by increased Ang II. Male type 1 diabetic OVE26 and wild-type mice...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Qian, Ling-Bo, Jiang, Sai-Zhi, Tang, Xiao-Qiang, Zhang, Jian, Liang, Ya-Qin, Yu, Hai-Tao, Chen, Jing, Xu, Zheng, Liu, Rui-Ming, Keller, Bradley B., Ji, Hong-Lei, Cai, Lu
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739764/
https://ncbi.nlm.nih.gov/pubmed/29290979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21302
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados