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Metformin alleviates nickel-induced autophagy and apoptosis via inhibition of hexokinase-2, activating lipocalin-2, in human bronchial epithelial cells

Autophagy is an intracellular recycling and degradation process for regulating tumor progression, survival and drug resistance. Nickel compounds have been identified as human carcinogens. However, the role of nickel-induced autophagy in lung carcinogenesis has not yet been fully elucidated. In this...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Kang, Yu-Ting, Hsu, Wen-Cheng, Wu, Chih-Hsien, Hsin, I-Lun, Wu, Pei-Ru, Yeh, Kun-Tu, Ko, Jiunn-Liang
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739657/
https://ncbi.nlm.nih.gov/pubmed/29285270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22317
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