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Metformin alleviates nickel-induced autophagy and apoptosis via inhibition of hexokinase-2, activating lipocalin-2, in human bronchial epithelial cells

Autophagy is an intracellular recycling and degradation process for regulating tumor progression, survival and drug resistance. Nickel compounds have been identified as human carcinogens. However, the role of nickel-induced autophagy in lung carcinogenesis has not yet been fully elucidated. In this...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kang, Yu-Ting, Hsu, Wen-Cheng, Wu, Chih-Hsien, Hsin, I-Lun, Wu, Pei-Ru, Yeh, Kun-Tu, Ko, Jiunn-Liang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739657/
https://ncbi.nlm.nih.gov/pubmed/29285270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22317
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