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Dietary polyphenols influence antimetabolite agents: methotrexate, 6-mercaptopurine and 5-fluorouracil in leukemia cell lines

Polyphenols have been previously shown to sensitize leukemia cell lines to topoisomerase inhibitors. Here, we assess the effects of five polyphenols when used alone and in combination with antimetabolites: methotrexate, 6-mercaptopurine and 5-fluorouracil; in lymphoid and myeloid leukemia cells line...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Mahbub, Amani, Le Maitre, Christine, Haywood-Small, Sarah, Cross, Neil, Jordan-Mahy, Nicola
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739607/
https://ncbi.nlm.nih.gov/pubmed/29285220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20501
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