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Dietary polyphenols influence antimetabolite agents: methotrexate, 6-mercaptopurine and 5-fluorouracil in leukemia cell lines

Polyphenols have been previously shown to sensitize leukemia cell lines to topoisomerase inhibitors. Here, we assess the effects of five polyphenols when used alone and in combination with antimetabolites: methotrexate, 6-mercaptopurine and 5-fluorouracil; in lymphoid and myeloid leukemia cells line...

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Publicado en:Oncotarget
Autores principales: Mahbub, Amani, Le Maitre, Christine, Haywood-Small, Sarah, Cross, Neil, Jordan-Mahy, Nicola
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739607/
https://ncbi.nlm.nih.gov/pubmed/29285220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20501
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