Polyphenols enhance the activity of alkylating agents in leukaemia cell lines

Polyphenols have been shown to sensitize solid tumours to alkylating agents such as cisplatin, and induce apoptosis and/or cell-cycle arrest. Here, we assess the effects of five polyphenols alone and in combination with three alkylating agents: cisplatin, cyclophosphamide and chlorambucil in lymphoi...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Mahbub, Amani A., Maitre, Christine L. Le, Haywood-Small, Sarah, Cross, Neil A., Jordan-Mahy, Nicola
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2019
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6642044/
https://ncbi.nlm.nih.gov/pubmed/31360305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27068
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