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Calcium–NFAT transcriptional signalling in T cell activation and T cell exhaustion
A cornerstone of the adaptive immune response is the T cell receptor (TcR)–calcium–calcineurin signalling pathway leading to T cell activation. The ‘nuclear factor of activated T cells’ proteins NFAT1, NFAT2, and NFAT4 are transcription factors that promote expression of a panel of genes required fo...
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| Pubblicato in: | Cell Calcium |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5739523/ https://ncbi.nlm.nih.gov/pubmed/28153342 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2017.01.014 |
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