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NF-κB is crucial in proximal T-cell signaling for calcium influx and NFAT activation

In the accepted model of T-cell activation, parallel signal transduction pathways activate the transcription factors NF-κB, NFAT and AP-1 to drive clonal expansion of T cells in response to antigen. Genome-wide transcriptional profiling following antigen-induced CD8(+) T-cell activation in C57BL/6 m...

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Bronk, Crystina C., Yoder, Sean, Hopewell, Emily L., Yang, Shengyu, Celis, Esteban, Yu, Xue-Zhong, Beg, Amer A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4261047/
https://ncbi.nlm.nih.gov/pubmed/25251667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201444904
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