Estimation of tamoxifen metabolite concentrations in the blood of breast cancer patients through CYP2D6 genotype activity score

Tamoxifen, a prodrug used for adjuvant breast cancer therapy, requires conversion to the active metabolite endoxifen through CYP 2D6. We aimed to construct an algorithm to predict endoxifen concentrations based on a patient’s CYP 2D6 genotype, demographic factors, and comedication use. Eighty-eight...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Breast Cancer Res Treat
Hoofdauteurs: Wu, Alan H. B., Lorizio, Wendy, Tchu, Simone, Lynch, Kara, Gerona, Roy, Ji, Wuyang, Ruan, Weiming, Ruddy, Kathryn J., Desantis, Stephen D., Burstein, Harold J., Ziv, Elad
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739025/
https://ncbi.nlm.nih.gov/pubmed/22294487
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-012-1963-2
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items