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CYP2D6 Genotype Predicts Plasma Concentrations of Tamoxifen Metabolites in Ethiopian Breast Cancer Patients

Tamoxifen displays wide inter-individual variability (IIV) in its pharmacokinetics and treatment outcome. Data on tamoxifen pharmacokinetics and pharmacogenetics from black African breast cancer patient populations is lacking. We investigated the pharmacokinetic and pharmacogenetic profile of tamoxi...

詳細記述

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書誌詳細
出版年:Cancers (Basel)
主要な著者: Ahmed, Jemal Hussien, Makonnen, Eyasu, Fotoohi, Alan, Aseffa, Abraham, Howe, Rawleigh, Aklillu, Eleni
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6770728/
https://ncbi.nlm.nih.gov/pubmed/31547390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11091353
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