Population Pharmacokinetic, Pharmacogenetic, and Pharmacodynamic Analysis of Cyclophosphamide in Ethiopian Breast Cancer Patients

Cyclophosphamide (CPA) containing chemotherapy regimen is the standard of care for breast cancer treatment in sub-Saharan Africa. Wide inter-individual variations in pharmacokinetics (PK) of cyclophosphamide (CPA) influence the efficacy and toxicity of CPA containing chemotherapy. Data on the pharma...

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Bibliographic Details
Published in:Front Pharmacol
Main Authors: Ahmed, Jemal Hussien, Makonnen, Eyasu, Bisaso, Ronald Kuteesa, Mukonzo, Jackson Kijumba, Fotoohi, Alan, Aseffa, Abraham, Howe, Rawleigh, Hassan, Moustapha, Aklillu, Eleni
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Pharmacology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7191301/
https://ncbi.nlm.nih.gov/pubmed/32390827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2020.00406
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