Tamoxifen Metabolite Concentrations, CYP2D6 Genotype and Breast Cancer Outcomes

We explored whether breast cancer outcomes are associated with endoxifen and other metabolites of tamoxifen, and to examine potential correlates of endoxifen concentrations including CYP2D6 metabolizer phenotype and body mass index (BMI). Tamoxifen, endoxifen, 4-hydroxytamoxifen and N-desmethyltamox...

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Main Authors: Madlensky, Lisa, Natarajan, Loki, Tchu, Simone, Pu, Minya, Mortimer, Joanne, Flatt, Shirley W., Nikoloff, D. Michele, Hillman, Grantland, Fontecha, Marcel R., Lawrence, H. Jeffrey, Parker, Barbara A., Wu, Alan H.B., Pierce, John P.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081375/
https://ncbi.nlm.nih.gov/pubmed/21430657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2011.32
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