Tenuigenin protects dopaminergic neurons from inflammation via suppressing NLRP3 inflammasome activation in microglia

BACKGROUND: Emerging evidence indicates that nod-like receptor family, pyrin domain-containing 3 (NLRP3) inflammasome-induced inflammation plays a crucial role in the pathogenesis of Parkinson’s disease (PD). Thus, inhibition of NLRP3 inflammasome activation may offer a therapeutic benefit in the tr...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Neuroinflammation
Auteurs principaux: Fan, Zheng, Liang, Zhigang, Yang, Hui, Pan, Yuting, Zheng, Yan, Wang, Xiaomin
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738892/
https://ncbi.nlm.nih.gov/pubmed/29262843
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-1036-x
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