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In silico prediction of chemical mechanism of action via an improved network‐based inference method
BACKGROUND AND PURPOSE: Deciphering chemical mechanism of action (MoA) enables the development of novel therapeutics (e.g. drug repositioning) and evaluation of drug side effects. Development of novel computational methods for chemical MoA assessment under a systems pharmacology framework would acce...
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| Publicado no: | Br J Pharmacol |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5738663/ https://ncbi.nlm.nih.gov/pubmed/27646592 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13629 |
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