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Prediction of Drug-Target Interactions and Drug Repositioning via Network-Based Inference
Drug-target interaction (DTI) is the basis of drug discovery and design. It is time consuming and costly to determine DTI experimentally. Hence, it is necessary to develop computational methods for the prediction of potential DTI. Based on complex network theory, three supervised inference methods w...
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Hauptverfasser: | , , , , , , , , |
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Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
Public Library of Science
2012
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3349722/ https://ncbi.nlm.nih.gov/pubmed/22589709 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002503 |
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