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Prediction of Drug-Target Interactions and Drug Repositioning via Network-Based Inference

Drug-target interaction (DTI) is the basis of drug discovery and design. It is time consuming and costly to determine DTI experimentally. Hence, it is necessary to develop computational methods for the prediction of potential DTI. Based on complex network theory, three supervised inference methods w...

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Detalhes bibliográficos
Main Authors: Cheng, Feixiong, Liu, Chuang, Jiang, Jing, Lu, Weiqiang, Li, Weihua, Liu, Guixia, Zhou, Weixing, Huang, Jin, Tang, Yun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349722/
https://ncbi.nlm.nih.gov/pubmed/22589709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002503
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