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Prediction of Drug-Target Interactions and Drug Repositioning via Network-Based Inference

Drug-target interaction (DTI) is the basis of drug discovery and design. It is time consuming and costly to determine DTI experimentally. Hence, it is necessary to develop computational methods for the prediction of potential DTI. Based on complex network theory, three supervised inference methods w...

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Detaylı Bibliyografya
Asıl Yazarlar: Cheng, Feixiong, Liu, Chuang, Jiang, Jing, Lu, Weiqiang, Li, Weihua, Liu, Guixia, Zhou, Weixing, Huang, Jin, Tang, Yun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2012
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349722/
https://ncbi.nlm.nih.gov/pubmed/22589709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1002503
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