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The emergence of acid ceramidase as a therapeutic target for acute myeloid leukemia

INTRODUCTION: Acute myeloid leukemia (AML) is the most common adult leukemia. Only a fraction of AML patients will survive with existing chemotherapy regimens. Hence, there is an urgent and unmet need to identify novel targets and develop better therapeutics in AML. In the past decade, the field of...

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Опубликовано в: :Expert Opin Ther Targets
Главные авторы: Tan, Su-Fern, Pearson, Jennifer M., Feith, David J., Loughran, Thomas P.
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738025/
https://ncbi.nlm.nih.gov/pubmed/28434262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14728222.2017.1322065
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