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The emergence of acid ceramidase as a therapeutic target for acute myeloid leukemia

INTRODUCTION: Acute myeloid leukemia (AML) is the most common adult leukemia. Only a fraction of AML patients will survive with existing chemotherapy regimens. Hence, there is an urgent and unmet need to identify novel targets and develop better therapeutics in AML. In the past decade, the field of...

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Pubblicato in:Expert Opin Ther Targets
Autori principali: Tan, Su-Fern, Pearson, Jennifer M., Feith, David J., Loughran, Thomas P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738025/
https://ncbi.nlm.nih.gov/pubmed/28434262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14728222.2017.1322065
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