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The microenvironment in myelodysplastic syndromes: niche-mediated disease initiation and progression

Myelodysplastic syndromes (MDS) are clonal disorders of hematopoietic stem and progenitor cells and represent the most common cause of acquired marrow failure. Hallmarked by ineffective hematopoiesis, dysplastic marrow, and risk of transformation to acute leukemia, MDS remains a poorly treated disea...

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Vydáno v:Exp Hematol
Hlavní autoři: Li, Allison J., Calvi, Laura M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737956/
https://ncbi.nlm.nih.gov/pubmed/28826860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2017.08.003
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