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Gold nanoparticle size and shape effects on cellular uptake and intracellular distribution of siRNA nanoconstructs

Gold nanoparticles (AuNPs) show potential for transfecting target cells with small interfering RNA (siRNA), but the influence of key design parameters such as the size and shape of the particle core is incomplete. This paper describes a side-by-side comparison of the in vitro response of U87 gliobla...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Bioconjug Chem
Hauptverfasser: Yue, Jun, Feliciano, Timothy Joel, Li, Wenlong, Lee, Andrew, Odom, Teri W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737752/
https://ncbi.nlm.nih.gov/pubmed/28574255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.bioconjchem.7b00252
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