Diverse antigenic site targeting of influenza hemagglutinin in the murine antibody recall response to A(H1N1)pdm09 virus

Here we define the epitopes on HA that are targeted by a group of 9 recombinant monoclonal antibodies (rmAbs) isolated from memory B cells of mice, immunized by infection with A(H1N1)pdm09 virus followed by a seasonal TIV boost. These rmAbs were all reactive against the HA1 region of HA, but display...

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Publicado en:Virology
Main Authors: Wilson, Jason R., Guo, Zhu, Tzeng, Wen-Pin, Garten, Rebecca J., Xiyan, Xu, Blanchard, Elisabeth G., Blanchfield, Kristy, Stevens, James, Katz, Jacqueline M., York, Ian A.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737639/
https://ncbi.nlm.nih.gov/pubmed/26318247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.08.004
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