Recombinant influenza H7 hemagglutinins induce lower neutralizing antibody titers in mice than do seasonal hemagglutinins

BACKGROUND: Vaccines against avian influenza viruses often require high hemagglutinin (HA) doses or adjuvants to achieve serological titers associated with protection against disease. In particular, viruses of the H7 subtype frequently do not induce strong antibody responses following immunization....

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Bibliographische Detailangaben
Veröffentlicht in:Influenza Other Respir Viruses
Hauptverfasser: Blanchfield, Kristy, Kamal, Ram P, Tzeng, Wen-Pin, Music, Nedzad, Wilson, Jason R, Stevens, James, Lipatov, Aleksander S, Katz, Jacqueline M, York, Ian A
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2014
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262278/
https://ncbi.nlm.nih.gov/pubmed/25213778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/irv.12285
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