Recombinant influenza H7 hemagglutinins induce lower neutralizing antibody titers in mice than do seasonal hemagglutinins

BACKGROUND: Vaccines against avian influenza viruses often require high hemagglutinin (HA) doses or adjuvants to achieve serological titers associated with protection against disease. In particular, viruses of the H7 subtype frequently do not induce strong antibody responses following immunization....

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Publicado en:Influenza Other Respir Viruses
Autores principales: Blanchfield, Kristy, Kamal, Ram P, Tzeng, Wen-Pin, Music, Nedzad, Wilson, Jason R, Stevens, James, Lipatov, Aleksander S, Katz, Jacqueline M, York, Ian A
Formato: Artigo
Lenguaje:Inglês
Publicado: BlackWell Publishing Ltd 2014
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4262278/
https://ncbi.nlm.nih.gov/pubmed/25213778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/irv.12285
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