Structural Stability of Influenza A(H1N1)pdm09 Virus Hemagglutinins

The noncovalent interactions that mediate trimerization of the influenza hemagglutinin (HA) are important determinants of its biological activities. Recent studies have demonstrated that mutations in the HA trimer interface affect the thermal and pH sensitivities of HA, suggesting a possible impact...

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Bibliographic Details
Main Authors: Yang, Hua, Chang, Jessie C., Guo, Zhu, Carney, Paul J., Shore, David A., Donis, Ruben O., Cox, Nancy J., Villanueva, Julie M., Klimov, Alexander I., Stevens, James
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993803/
https://ncbi.nlm.nih.gov/pubmed/24522930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02278-13
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