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Structural Stability of Influenza A(H1N1)pdm09 Virus Hemagglutinins

The noncovalent interactions that mediate trimerization of the influenza hemagglutinin (HA) are important determinants of its biological activities. Recent studies have demonstrated that mutations in the HA trimer interface affect the thermal and pH sensitivities of HA, suggesting a possible impact...

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Détails bibliographiques
Auteurs principaux: Yang, Hua, Chang, Jessie C., Guo, Zhu, Carney, Paul J., Shore, David A., Donis, Ruben O., Cox, Nancy J., Villanueva, Julie M., Klimov, Alexander I., Stevens, James
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3993803/
https://ncbi.nlm.nih.gov/pubmed/24522930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02278-13
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