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Comparative analysis of chimeric ZFP-, TALE- and Cas9-piggyBac transposases for integration into a single locus in human cells

Integrating DNA delivery systems hold promise for many applications including treatment of diseases; however, targeted integration is needed for improved safety. The piggyBac (PB) transposon system is a highly active non-viral gene delivery system capable of integrating defined DNA segments into hos...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Luo, Wentian, Galvan, Daniel L., Woodard, Lauren E., Dorset, Dan, Levy, Shawn, Wilson, Matthew H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737283/
https://ncbi.nlm.nih.gov/pubmed/28666380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx572
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