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Dicer-independent processing of small RNA duplexes: mechanistic insights and applications

MicroRNAs (miRNAs) play a pivotal role in the regulation of cellular gene expression via the conserved RNA interference (RNAi) mechanism. Biogenesis of the unusual miR-451 does not require Dicer. This molecule is instead processed by the Argonaute 2 (Ago2) enzyme. Similarly, unconventional short hai...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Herrera-Carrillo, Elena, Berkhout, Ben
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737282/
https://ncbi.nlm.nih.gov/pubmed/28977573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx779
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