HDAC2 and HDAC5 Up-Regulations Modulate Survivin and miR-125a-5p Expressions and Promote Hormone Therapy Resistance in Estrogen Receptor Positive Breast Cancer Cells

Intrinsic or acquired resistance to hormone therapy is frequently reported in estrogen receptor positive (ER(+)) breast cancer patients. Even though dysregulations of histone deacetylases (HDACs) are known to promote cancer cells survival, the role of different HDACs in the induction of hormone ther...

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Publicado no:Front Pharmacol
Main Authors: Huang, Wen-Tsung, Tsai, Yu-Hsuan, Chen, Shang-Hung, Kuo, Ching-Wen, Kuo, Yao-Lung, Lee, Kuo-Ting, Chen, Wen-Chung, Wu, Pei Chih, Chuang, Chun-Yu, Cheng, Siao Muk, Lin, Chun-Hui, Leung, Euphemia Yee, Chang, Yung-Chieh, Cheung, Chun Hei Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736991/
https://ncbi.nlm.nih.gov/pubmed/29326587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00902
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