HDAC Inhibitors Target HDAC5, Upregulate MicroRNA-125a-5p, and Induce Apoptosis in Breast Cancer Cells

Histone deacetylase inhibitors (HDACi) are novel clinical anticancer drugs that inhibit HDAC gene expression and induce cell apoptosis in human cancers. Nevertheless, the detailed mechanism or the downstream HDAC targets by which HDACi mediates apoptosis in human breast cancer cells remains unclear....

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Ther
Päätekijät: Hsieh, Tsung-Hua, Hsu, Chia-Yi, Tsai, Cheng-Fang, Long, Cheng-Yu, Wu, Chin-Hu, Wu, Deng-Chyang, Lee, Jau-Nan, Chang, Wei-Chun, Tsai, Eing-Mei
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2015
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395776/
https://ncbi.nlm.nih.gov/pubmed/25531695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2014.247
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