Delivery of a survivin promoter-driven antisense survivin-expressing plasmid DNA as a cancer therapeutic: a proof-of-concept study

Survivin is a member of the inhibitor-of-apoptosis proteins family. It is overexpressed in many different cancer types but not in the differentiated normal tissue. In addition, overexpression of survivin promotes cancer cell survival and induces chemotherapeutic drug resistance, making it an attract...

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Bibliographic Details
Published in:Onco Targets Ther
Main Authors: Lin, Kun-Yuan, Cheng, Siao Muk, Tsai, Shing-Ling, Tsai, Ju-Ya, Lin, Chun-Hui, Cheung, Chun Hei Antonio
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2016
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862386/
https://ncbi.nlm.nih.gov/pubmed/27217778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S101209
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