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Delivery of a survivin promoter-driven antisense survivin-expressing plasmid DNA as a cancer therapeutic: a proof-of-concept study

Survivin is a member of the inhibitor-of-apoptosis proteins family. It is overexpressed in many different cancer types but not in the differentiated normal tissue. In addition, overexpression of survivin promotes cancer cell survival and induces chemotherapeutic drug resistance, making it an attract...

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Publicat a:Onco Targets Ther
Autors principals: Lin, Kun-Yuan, Cheng, Siao Muk, Tsai, Shing-Ling, Tsai, Ju-Ya, Lin, Chun-Hui, Cheung, Chun Hei Antonio
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862386/
https://ncbi.nlm.nih.gov/pubmed/27217778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S101209
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