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Delivery of a survivin promoter-driven antisense survivin-expressing plasmid DNA as a cancer therapeutic: a proof-of-concept study

Survivin is a member of the inhibitor-of-apoptosis proteins family. It is overexpressed in many different cancer types but not in the differentiated normal tissue. In addition, overexpression of survivin promotes cancer cell survival and induces chemotherapeutic drug resistance, making it an attract...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Lin, Kun-Yuan, Cheng, Siao Muk, Tsai, Shing-Ling, Tsai, Ju-Ya, Lin, Chun-Hui, Cheung, Chun Hei Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4862386/
https://ncbi.nlm.nih.gov/pubmed/27217778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S101209
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