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Human intrahepatic ILC2 are IL-13(positive )amphiregulin(positive) and their frequency correlates with model of end stage liver disease score

INTRODUCTION: Innate lymphoid cells (ILC) have been implicated in the initiation of inflammation and fibrosis in mice. However, ILC have not been characterized in inflamed human liver tissue. METHODS: Human intrahepatic lymphocytes were isolated by mechanical digestion and phenotyped by flow cytomet...

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Vydáno v:PLoS One
Hlavní autoři: Jeffery, Hannah C., McDowell, Patrick, Lutz, Philipp, Wawman, Rebecca E., Roberts, Sheree, Bagnall, Chris, Birtwistle, Jane, Adams, David H., Oo, Ye Htun
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5736232/
https://ncbi.nlm.nih.gov/pubmed/29261670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188649
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