Biliary epithelium and liver B cells exposed to bacteria activate intrahepatic MAIT cells through MR1

BACKGROUND & AIMS: Mucosal-Associated Invariant T (MAIT) cells are innate-like T cells characterised by the invariant TCR-chain, Vα7.2-Jα33, and are restricted by MR1, which presents bacterial vitamin B metabolites. They are important for antibacterial immunity at mucosal sites; however, detaile...

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Dades bibliogràfiques
Publicat a:J Hepatol
Autors principals: Jeffery, Hannah C., van Wilgenburg, Bonnie, Kurioka, Ayako, Parekh, Krishan, Stirling, Kathryn, Roberts, Sheree, Dutton, Emma E., Hunter, Stuart, Geh, Daniel, Braitch, Manjit K., Rajanayagam, Jeremy, Iqbal, Tariq, Pinkney, Thomas, Brown, Rachel, Withers, David R., Adams, David H., Klenerman, Paul, Oo, Ye H.
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4822535/
https://ncbi.nlm.nih.gov/pubmed/26743076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2015.12.017
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