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Metal-free, Regio-, and Stereo-Controlled Hydrochlorination and Hydrobromination of Ynones and Ynamides

[Image: see text] We developed an atom-economical and metal-free method for the regio- and stereo-selective hydrohalogenation of ynones and ynamides using easy to handle DMPU/HX (X = Br or Cl) reagents. The reaction operates under mild conditions and a range of functional groups is well tolerated. W...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Org Chem
Prif Awduron: Zeng, Xiaojun, Lu, Zhichao, Liu, Shiwen, Hammond, Gerald B., Xu, Bo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Chemical Society 2017
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735994/
https://ncbi.nlm.nih.gov/pubmed/29166765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.7b02257
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