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Hippocampal calpain is required for the consolidation and reconsolidation but not extinction of contextual fear memory

Memory consolidation, reconsolidation, and extinction have been shown to share similar molecular signatures, including new gene expression. Calpain is a Ca(2+)-dependent protease that exerts its effects through the proteolytic cleavage of target proteins. Neuron-specific conditional deletions of cal...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Brain
Prif Awduron: Nagayoshi, Taikai, Isoda, Kiichiro, Mamiya, Nori, Kida, Satoshi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735908/
https://ncbi.nlm.nih.gov/pubmed/29258546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-017-0341-8
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