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Hippocampal calpain is required for the consolidation and reconsolidation but not extinction of contextual fear memory

Memory consolidation, reconsolidation, and extinction have been shown to share similar molecular signatures, including new gene expression. Calpain is a Ca(2+)-dependent protease that exerts its effects through the proteolytic cleavage of target proteins. Neuron-specific conditional deletions of cal...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Nagayoshi, Taikai, Isoda, Kiichiro, Mamiya, Nori, Kida, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735908/
https://ncbi.nlm.nih.gov/pubmed/29258546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-017-0341-8
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