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PARP-1 activity is required for the reconsolidation and extinction of contextual fear memory

BACKGROUND: Memory consolidation, reconsolidation, and extinction have been shown to require new gene expression. Poly ADP-ribosylation mediated by poly (ADP-ribose) polymerase-1 (PARP-1) is known to regulate transcription through histone modification. Recent studies have suggested that PARP-1 posit...

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Detalhes bibliográficos
Publicado no:Mol Brain
Main Authors: Inaba, Hiroyoshi, Tsukagoshi, Akinori, Kida, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4608138/
https://ncbi.nlm.nih.gov/pubmed/26471780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0153-7
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