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Src family kinase phosphorylation of the motor domain of the human kinesin-5, Eg5

Spindle formation in mammalian cells requires precise spatial and temporal regulation of the kinesin-5, Eg5, which generates outward force to establish spindle bipolarity. Our results demonstrate that Eg5 is phosphorylated in cultured cells by Src family kinases (SFKs) at three sites in the motor he...

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Detalhes bibliográficos
Publicado no:Cytoskeleton (Hoboken)
Main Authors: Bickel, Kathleen G., Mann, Barbara J., Waitzman, Joshua S., Poor, Taylor A., Rice, Sarah E., Wadsworth, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735839/
https://ncbi.nlm.nih.gov/pubmed/28646493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cm.21380
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