Dendrimer-mediated delivery of N-acetyl cysteine to microglia in a mouse model of Rett syndrome

BACKGROUND: Rett syndrome (RTT) is a pervasive developmental disorder that is progressive and has no effective cure. Immune dysregulation, oxidative stress, and excess glutamate in the brain mediated by glial dysfunction have been implicated in the pathogenesis and worsening of symptoms of RTT. In t...

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Publicado en:J Neuroinflammation
Autores principales: Nance, Elizabeth, Kambhampati, Siva P., Smith, Elizabeth S., Zhang, Zhi, Zhang, Fan, Singh, Sarabdeep, Johnston, Michael V., Rangaramanujam, Kannan, Blue, Mary E., Kannan, Sujatha
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735803/
https://ncbi.nlm.nih.gov/pubmed/29258545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-017-1004-5
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