Twice Weekly Pulse and Daily Continuous Dose Erlotinib as Initial Treatment for Patients with EGFR-Mutant Lung Cancers and Brain Metastases

BACKGROUND: In a phase 1 study of pulse-continuous dose erlotinib, no patient had disease progression in the central nervous system. This expansion cohort of the phase 1 study tests this same regimen in a cohort of individuals with EGFR-mutant lung cancers with untreated brain metastases. METHODS: P...

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Publicado no:Cancer
Main Authors: Arbour, Kathryn C., Kris, Mark G., Riely, Gregory J., Ni, Ai, Beal, Kathryn, Daras, Mariza, Hayes, Sara A., Young, Robert J., Rodriguez, Christopher R, Ahn, Linda, Pao, William, Yu, Helena A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5735028/
https://ncbi.nlm.nih.gov/pubmed/28940498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.30990
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