Sex-Specific Transcriptional Signatures in Human Depression

Major depressive disorder (MDD) is a leading cause of disease burden worldwide. While the incidence, symptoms and treatment of MDD all point toward major sex differences, the molecular mechanisms underlying this sexual dimorphism remain largely unknown. Here, combining differential expression and we...

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Vydáno v:Nat Med
Hlavní autoři: Labonté, Benoit, Engmann, Olivia, Purushothaman, Immanuel, Menard, Caroline, Wang, Junshi, Tan, Chunfeng, Scarpa, Joseph R, Moy, Gregory, Loh, Yong-Hwee E, Cahill, Michael, Lorsch, Zachary S, Hamilton, Peter J., Calipari, Erin S, Hodes, Georgia E., Issler, Orna, Kronman, Hope, Pfau, Madeline, Obradovic, Aleksander, Dong, Yan, Neve, Rachel, Russo, Scott, Kazarskis, Andrew, Tamminga, Carol, Mechawar, Naguib, Turecki, Gustavo, Zhang, Bin, Shen, Li, Nestler, Eric J
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5734943/
https://ncbi.nlm.nih.gov/pubmed/28825715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4386
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