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In vitro cardiotoxicity assessment of environmental chemicals using an organotypic human induced pluripotent stem cell-derived model

An important target area for addressing data gaps through in vitro screening is the detection of potential cardiotoxicants. Despite the fact that current conservative estimates relate at least 23% of all cardiovascular disease cases to environmental exposures, the identities of the causative agents...

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Библиографические подробности
Опубликовано в: :Toxicol Appl Pharmacol
Главные авторы: Sirenko, Oksana, Grimm, Fabian A., Ryan, Kristen R., Iwata, Yasuhiro, Chiu, Weihsueh A., Parham, Frederick, Wignall, Jessica A., Anson, Blake, Cromwell, Evan F., Behl, Mamta, Rusyn, Ivan, Tice, Raymond R.
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5734940/
https://ncbi.nlm.nih.gov/pubmed/28259702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2017.02.020
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