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Molecular dynamics simulation unveils the conformational flexibility of the interdomain linker in the bacterial transcriptional regulator GabR from Bacillus subtilis bound to pyridoxal 5’-phosphate

GabR from Bacillus subtilis is a transcriptional regulator belonging to the MocR subfamily of the GntR regulators. The structure of the MocR regulators is characterized by the presence of two domains: i) a N-terminal domain, about 60 residue long, possessing the winged-Helix-Turn-Helix (wHTH) archit...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Milano, Teresa, Gulzar, Adnan, Narzi, Daniele, Guidoni, Leonardo, Pascarella, Stefano
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5734734/
https://ncbi.nlm.nih.gov/pubmed/29253008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0189270
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